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mne_simu

Overview​

mne_simu generates simulated MEG/EEG raw data from a forward solution. A sinusoidal signal is placed at a specified source location and projected through the forward model, with optional additive noise from a noise covariance matrix. This is useful for testing inverse methods and validating processing pipelines.

This is a C++ port of the original MNE-C tool by Matti Hämäläinen.

Usage​

mne_simu [options]

Options​

OptionDescription
--fwd <file>Forward solution FIFF file
--raw <file>Raw FIFF file (for channel info and sampling rate)
--cov <file>Noise covariance FIFF file (optional)
--source <idx>Source index to activate (default: 0)
--snr <value>Signal-to-noise ratio in dB (default: 20)
--duration <sec>Duration of simulation in seconds (default: 1.0)
--freq <Hz>Signal frequency in Hz (default: 10.0)
--out <file>Output simulated raw FIFF file
--helpPrint help
--versionPrint version

Description​

The simulation generates a sinusoidal time course at a single source location, projects it through the forward solution to produce sensor-level data, and optionally adds Gaussian noise scaled to achieve the specified SNR. The channel configuration and sampling rate are taken from the template raw file.

Workflow Context​

Simulation is used for:

  • Inverse method validation: Generate data with known source location and verify that inverse methods recover it correctly.
  • Pipeline testing: Test processing pipelines end-to-end with controlled data.
  • SNR studies: Evaluate how source localization accuracy depends on noise levels.

The typical workflow is:

  1. Compute forward solution → mne_forward_solution
  2. Generate simulated data → mne_simu
  3. Apply inverse method → mne_compute_mne or mne_dipole_fit
  4. Compare recovered source location with ground truth

Example​

# Simulate 2 seconds of 10 Hz activity at source 42 with 15 dB SNR
mne_simu --fwd sam-fwd.fif --raw sam-raw.fif --cov noise-cov.fif \
--source 42 --snr 15 --duration 2.0 --freq 10.0 --out simulated-raw.fif